David L. DeMets Lectures

2022 DeMets Lectures

The Department of Biostatistics and Medical Informatics will host the DeMets Lectures in Health and Quantitative Investigation in person November 3-4, 2022.


Dr. Michael Proschan, Mathematical Statistician, Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health

Dates, Times, and Locations:

November 3: General Lecture: Subgroup Mortality Results for Remdesivir in COVID-19: Real or the Play of Chance?
3:30-4:45 PM – Health Sciences Learning Center, Room 1335. Reception to follow.

November 4: Research Lecture: Data-Driven Monitoring of Clinical Trials in the COVID-19 Era
Noon-1:00 PM – Biotechnology Center Auditorium


Speaker Bio:

Michael Proschan has been a Mathematical Statistician in the Biostatistics Research Branch at the National Institute of Allergy and Infectious Diseases since January of 2006. Prior to coming to NIAID, he spent 16 years at the National Heart, Lung, and Blood Institute, where he worked on many large clinical trials. His research interests include monitoring and adaptive methods in clinical trials, and he co-authored the book: Statistical Monitoring of Clinical Trials: A Unified Approach, with Gordon Lan and Janet Wittes (Springer, 2006). His work in adaptive clinical trials includes the use of permutation/re-randomization tests to analyze the results of adaptive trials, and some of this work is included in his most recent book, co-authored with Pamela Shaw: Essentials of Probability Theory for Statisticians (CRC Press, 2016).

Dr. Proschan received his Ph.D. in Statistics from Florida State University in 1989, M.S. in Statistics from Stanford University in 1982, and B.S. in Statistics and Mathematics (double major) from Florida State University in 1980. He is a Fellow of the American Statistical Association. He has taught or been a teaching assistant for statistics and mathematics courses at (from most to least recent) George Washington University, Johns Hopkins University, The Foundation for Advanced Education in the Sciences, Florida State University, Stanford University, Palm Beach Junior College, and Tallahassee Community College.

The Lectures

The David L. DeMets Lectures in Health and Quantitative Investigation are a pair of lectures held on a Thursday and Friday each November.

These lectures acknowledge Dr. DeMets’ research accomplishments in forwarding the design, monitoring, analysis, and presentation of clinical trials.

The first lecture is a research/overview talk is accessible to a general biomedical/public health audience. Ideally, it will highlight in one or more ways critical and impactful contributions from quantitative methodological areas (e.g., biostatistics and/or biomedical informatics) to discoveries in biomedicine, and/or advancement of human/public health. The second lecture is a world-class research talk in biostatistics or biomedical informatics.

The lecturer chosen each year exemplifies the “David DeMets Model of Biomedical Research” with rigorous development and application of quantitative methodological principles, married with deep engagement in an area of biomedical investigation.

Past DeMets Lectures Events

2020 and 2021 lectures were cancelled because of SARS-CoV-2.

2019 Lecture Information – Dr. Richard Landis

2018 Lecture Information – Speaker cancelled

2017 Lecture Information – Dr. Rob Tishirani

2016 Lecture Information – Dr. David Heckerman

2015 Lecture Information – Dr. Thomas R. Fleming