Dr. Sündüz Keleş and her graduate student, Ye Zheng, have developed FreeHi-C (fragment interactions empirical estimation for fast simulation of Hi-C data), a way to generate simulated Hi-C data which is published in Nature – https://www.nature.com/articles/s41592-019-0624-3
As well, there is a nice bio of Sündüz –
https://www.nature.com/articles/s41592-019-0696-0